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Research Paper | Biochemistry Science | India | Volume 3 Issue 12, December 2014

Effect of Shilajit on Testosterone Induced Benign Prostrate Hyperplasia in Rats

Aditya Vikas Sakhare ^[4] | Suraj Ashok Bhagat ^[3]

Abstract: Many plants have shown to improve uncontrolled growth of the prostate gland and improve urinary tract symptoms, which are associated with benign prostatic hyperplasia. Main component of those plants were fatty acids, fulvic acids and dibenzo alpha pyrones and traces minerals also some antioxidants drugs shows protective effect on BPH. Our study to investigate weather shilajit prevents testosterone induced prostatic hyperplasia in rat. Rats were divided into negative control group and testosterone induced prostatic hyperplasia groups (positive control, finasteride treated, low dose of shilajit and high dose of shilajit). All drug and testosterone treatment was given for 14 days. Rats were weighed before and after initiation of an experiment. Prostate weight and body weight ratio (pw/bw) and percentage of inhibition were calculated. Rats were sacrificed under light ether anaesthesia. Both doses of shilajit have significantly inhibited the elevation in prostate weight, doses of shilajit and finasteride showed protective against testosterone induced prostatic hyperplasia in rats.

Keywords: SHILAJIT, TESTOSTERONE, PROSTATIC, HYPERPLASIA

Edition: Volume 3 Issue 12, December 2014,

Pages: 674 - 676

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