International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 138

M.Tech / M.E / PhD Thesis | Biochemistry Science | Nigeria | Volume 5 Issue 2, February 2016


Effect of Methanol Extract of Carica papaya Seed on Some Hormone Function in Male Albino Rats

Reuben A. | Wurochekke A. U. | Mahmoud S. J.


Abstract: In this study, the anti-fertility activity of the methanolic seed extract of Carica papaya was investigated. Phytochemical screening of crude extract revealed the presence of alkaloids, flavonoids, glycosides, saponins and tannins while anthraquinone and phlobatannins were found to be absent. The study was conducted on 25 healthy male albino rats following oral administration of 100 mg/kg body weight, 200 mg/kg body weight, 400 mg/kg body weight and 800mg/kg body weight methanolic seed extract for the period of 7days. Epididymidal sperm count, total motility and viability, serum testosterone, luteinizing hormone, follicle stimulating hormone and prolactin were studied. There was a significant p<0.05 reduction in sperm counts and viability, testosterone and luteinizing hormone as compared to the control group. While there was elevated serum level of follicle stimulating hormone and Prolactin as compared to the control group. These results suggest that methanolic seed extract of Carica papaya posses anti-fertility activities which could impair spermatogenesis, hormonal synthesis and other functions which might lead to infertility.


Keywords: Carica papaya, Phytochemical screening, Anti-fertility activity, Hormones, Male rats


Edition: Volume 5 Issue 2, February 2016,


Pages: 387 - 389

Effect of Methanol Extract of Carica papaya Seed on Some Hormone Function in Male Albino Rats


How to Cite this Article?

Reuben A., Wurochekke A. U., Mahmoud S. J., "Effect of Methanol Extract of Carica papaya Seed on Some Hormone Function in Male Albino Rats", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=NOV161149, Volume 5 Issue 2, February 2016, 387 - 389, #ijsrnet

How to Share this Article?

Enter Your Email Address




Similar Articles with Keyword 'Phytochemical screening'

Downloads: 155

Research Paper, Biochemistry Science, India, Volume 5 Issue 6, June 2016

Pages: 810 - 814

Antibacterial Activity and Screening of Antibacterial Compounds of Costus pictus D.Don Using GC-MS

Ramya R [6] | Dhamotharan R

Share this Article

Downloads: 99

Research Paper, Biochemistry Science, Nigeria, Volume 3 Issue 12, December 2014

Pages: 2658 - 2661

Phytochemical Screening and Antibacterial Activities of Leaf Extracts of Terminalia catappa (Umbrella Tree)

Kankia H. I. [2]

Share this Article


Top