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Comparative Studies | Chemistry | Egypt | Volume 4 Issue 8, August 2015
Facile Synthesis and Structural Characterization of Some Phthalazin-1(2H)-one Derivatives as Antimicrobial Nucleosides and Reactive Dye
M. A. EL-Hashash | S. A. Rizk | M. A. Kadhim
Abstract: A new series of 2, 4-disubstituted phthalazin-1 (2H) -one derivatives was synthesized via nucleophilic attach of N-2 of phthalazin-1 (2H) -one derivatives on different monosuccharides. Synthesis of phthalazinone nucleosides were very effective as antimicrobial. . Also the phthalazinone moiety can be used in synthesis of reactive nucleosides and dyes that was chemically bonded with proteins and fibers respectively as afforded highly stability of dyestuff wool and cotton textiles. The structure of the prepared compounds were elucidated by physical and spectral data like FT-IR, 1H-NMR and 13C-NMR
Keywords: phthalazin-1 2H one, allyl-, propargyl-phthalazinone, nucleosides, reactive dye
Edition: Volume 4 Issue 8, August 2015,
Pages: 1350 - 1358
Similar Articles with Keyword 'allyl'
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Research Paper, Chemistry, Sudan, Volume 11 Issue 2, February 2022
Pages: 1270 - 1276Bioassay-Directed Isolation and Structural Characterization of Major Bioactive Compounds against E.coli from Cordia sinensis Lam.stem Bark Extract
Mustafa S. Koya [2] | Nada A. Elamin [2] | Zeinab A. Elrabei [2]
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Research Paper, Chemistry, Egypt, Volume 3 Issue 5, May 2014
Pages: 1701 - 1705Synthesis of Novel Phthalazines Containing Heterocyclic Moieties
Maher A. El-Hashash | Dalal B. Guirguis [2] | Nayera A.M. Abd El-Wahed | Mohamed A. Kadhim