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Review Papers | Pathology | Libya | Volume 6 Issue 3, March 2017
Macrophages: Contribution to Diseases Development and Progression
Dr. Nabeia Ali Gheryani [2] | Dr. Houssein H. Elmatri [2]
Abstract: Macrophages are versatile cells. They are derived from CD34+ bone marrow progenitors. Macrophages act as the first line of defence in the body against bacterial and viral infection. They also accumulate in acute and chronic inflammation and have an important role in healing and repair process. Studies have also indicated that macrophages participate in the development and progress of chronic disease such as rheumatoid arthritis and atherosclerosis. Many studies have suggested that macrophages play an important role in tumour cell invasion, growth, proliferation, and metastasis to distant organs. This review will summarise the role of macrophages in certain benign diseases. We also discuss the role of macrophages in tumour growth, progression and metastases.
Keywords: Macrophages, Tumour, Rheumatoid arthritis, Atherosclerosis, Inflammatory bowel diseases
Edition: Volume 6 Issue 3, March 2017,
Pages: 2057 - 2070
Similar Articles with Keyword 'Tumour'
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Case Studies, Pathology, India, Volume 11 Issue 7, July 2022
Pages: 978 - 980Nodular Swelling with Chronic Discharging Sinus on Leg - An Unusual Presentation of Eccrine Acrospiroma with Cytohistopathological Correlation
Dr. Krupa Jog [2] | Dr. Shailendra Munj | Dr. Varsha Munj [4]
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Research Paper, Pathology, India, Volume 11 Issue 12, December 2022
Pages: 936 - 939Role of FNAC in the Diagnosis of Salivary Gland Lesions
Dr. Naima Aziz | Dr Roop Rekha Das | Dr Mayuri Saikia