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Research Paper | Biochemistry Science | Volume 4 Issue 7, July 2015 | Pages: 1683 - 1686 | India
A Study on Assessment of Thyroid Stimulating Hormone and Insulin Resistance in Women with Polycystic Ovarian Syndrome
Abstract: Objective Polycystic ovarian syndrome (PCOS), the most common cause of infertility, is a disorder characterized by chronic anovulation, hyperandrogenism, hyperinsulinemia, and often presence of obesity. Obesity has been linked to endocrine disorders especially thyroid dysfunction. The present study was designed to assess thyroid stimulating hormone and insulin resistance in women with PCOS and to compare them with healthy women as controls. Material and Methods A comparative study including 30 women diagnosed as PCOS and 30 age and BMI matched healthy women as controls was conducted. The age group for the study was 18-35 years. Fasting blood samples were drawn to assess serum Insulin, HbA1c, triiodothyroxine (T3), thyroxine (T4), thyroid stimulating hormone (TSH) and fasting blood sugar (FBS). Insulin resistance (IR) was calculated by homeostasis model assessment (HOMA). Body Mass Index (BMI) was also calculated. Results A significant increase in fasting serum insulin (p
Keywords: PCOS, TSH, Insulin resistance
How to Cite?: B.V. Ravi, Sadaria Roshni Gokaldas, "A Study on Assessment of Thyroid Stimulating Hormone and Insulin Resistance in Women with Polycystic Ovarian Syndrome", Volume 4 Issue 7, July 2015, International Journal of Science and Research (IJSR), Pages: 1683-1686, https://www.ijsr.net/getabstract.php?paperid=SUB156755, DOI: https://dx.doi.org/10.21275/SUB156755