Serum Fructosamine Assessment, A Possible Index of Glycometabolism in Nomoglycaemic Subjects: An Observation in a Nigerian Tetiary Hospital

Adebayo Ayub-Eniola Ayodele, Musa Dungus Musa, Abdulrahim Halimat Amin, Simon Osita Obi, Alhaji Haruna Musa, Fatima Zakari Abacha, Abubakar Ahmed, John Wakbe Kankop, Mustafa Baba Zanna, Baba Usman Ahmadu

Abstract: . Serum fructosamine, albumin and fasting plasma glucose were measured in 500 apparently healthy non-diabetic, nomoglycaemic Nigerians. The concentration of fructosamine was found to be between 1.95 and 2.5 mmol/l with a mean (+ SD) of 2.16 + 0.23 mmol/l and correlated significantly with fasting plasma glucose (r = 0.67, P 0.05). No sex-related difference (P 0.05) was observed in male and female serum fructosamine levels, also no significance correlation was found between mean serum fructosamine and albumin concentrations (r = 0.13, P 0.05). This result showed that serum fructosamine concentration can be used as an index of glycometabolic control in normal and diabetic subjects in North-eastern Nigeria.

Keywords: Diabetes, fructosamine, albumin, glucose, glycation