International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 104 | Views: 219

Research Paper | Biochemistry Science | India | Volume 4 Issue 3, March 2015


Study of Plasma Homocysteine Level in Coronary Heart Disease Patients and Compare with Control

Sharma Hemlata [2] | Vyas Shalini [2] | Dr. Vyas R. K. | Dr. Chhaparwal Amit


Abstract: The study was conducted on 50 patients of coronary heart disease and 50 persons are healthy subjects between the age group 25-70 years of both sex. Homocysteine may increase cellular oxidative stress in which mitochondrial thioredoxin, and peroxidation are decreased and NADH oxidase activity is increased and generating peroxinitrite and nitrotyrosine in contractile protein which causes vascular dysfunction. Plasma homocysteine were measured by hplc grade kit with the help of HPLC. plasma homocysteine level of coronary heart disease patients showed a highly significant (p0.0001) relationship. Estimation of plasma homocysteine is reliable, economic and sensitive and it can be used in the proper management of chronic complications of coronary heart disease.


Keywords: Coronary heart disease, Homocysteine, HPLC, oxidative stress


Edition: Volume 4 Issue 3, March 2015,


Pages: 1479 - 1480


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