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Research Paper | Medicine Science | Nigeria | Volume 3 Issue 12, December 2014
Male Infertility Associated With Hyperprolactinaemia: Our Experience Using Bromocriptine in University of Maiduguri Teaching Hospital North Eastern Nigeria
Ibrahim A. G. [4] | Suleiman A. [2] | Alj N. | Mohammed B. S.
Abstract: Background: Hyperprolactinaemia is one of the established causes of infertility in both sexes, though rare in the male when taken in isolation. The cause in the majority though idiopathic, is amenable to drug treatment. Other causes include prolactinoma, antipsychotic drugs, and chronic liver disease. Hyperprolactinaemia suppresses spermatogenesis through various mechanisms, lowering the level of prolactin therefore improves semen parameters and fertility. Materials and methods: The study reviewed isolated hyperprolactinaemia associated male infertility in University of Maiduguri Teaching Hospital (UMTH) and State specialist Hospital Maiduguri from January 2007 to December 2011. Results: A total of 17 patients were studied age ranged from 27 52 years, with 11 idiopathic, 2 chronic liver diseases, 2 antipsychotic drugs medication and 1 each antithyroid drugs and multiples drugs abuse as the causes of hyperprolactinaemia. All patients received bromocriptine treatment with remarkable results. Conclusion: Hyperprolactinaemia associated male infertility exists in our environment and is amenable to bromocriptine treatment with good results.
Keywords: Male infertility, Hyperprolactinaemia, Bromocriptine treatment, Outcome
Edition: Volume 3 Issue 12, December 2014,
Pages: 2516 - 2518