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Original Research | Paediatrics | Volume 15 Issue 7, July 2026 | Pages: 354 - 360 | India
To Evaluate Effectiveness of Ferric Carboxymaltose in Treating Moderate Iron Deficiency Anemia in Pediatric Patients an Observational Study
Abstract: Background: Iron deficiency anemia (IDA) is a major public health concern in pediatric populations, particularly in developing countries such as India. Oral iron therapy is limited by poor compliance and gastrointestinal side effects. Intravenous ferric carboxymaltose (FCM) offers a potential alternative for rapid correction of anemia. Aim: To evaluate the effectiveness and safety of intravenous ferric carboxymaltose in children with moderate iron deficiency anemia. Methods: This study was conducted in 93 pediatric patients aged 1-18 years with moderate iron deficiency anemia. Baseline hemoglobin (Hb), mean corpuscular volume (MCV), and serum ferritin were assessed. Quantitative C-reactive protein (Q-CRP) and stool occult blood tests were performed to exclude inflammatory states and blood loss. Mentzer index was used to exclude thalassemia. All patients received a single dose of intravenous ferric carboxymaltose (15 mg/kg). Hemoglobin levels were reassessed after 21 days. Statistical analysis was performed using paired t-test. Results: The mean baseline hemoglobin was 8.02 ± 0.82 g/dL, which increased to 9.52 ± 1.08 g/dL after 21 days, with a mean rise of 1.50 ± 1.02 g/dL (p < 0.000001). A total of 94.6% of patients demonstrated improvement. No statistically significant correlation was observed between serum ferritin and hemoglobin levels (r = -0.09, p > 0.05). Adverse effects were minimal, occurring in 2.15% of patients. Conclusion: Intravenous ferric carboxymaltose appears to be a safe and effective option for short-term hematological improvement in children with moderate iron deficiency anemia. Further controlled studies with longer follow-up are warranted to confirm these findings.
Keywords: Iron deficiency anemia, Ferric carboxymaltose, Intravenous iron therapy
How to Cite?: Dr. Gaurav Mathur, Dr. Pankaj Kumar Singhal, Dr. Kavya R, Dr. Monika Dhakad, "To Evaluate Effectiveness of Ferric Carboxymaltose in Treating Moderate Iron Deficiency Anemia in Pediatric Patients an Observational Study", Volume 15 Issue 7, July 2026, International Journal of Science and Research (IJSR), Pages: 354-360, https://www.ijsr.net/getabstract.php?paperid=SR26704160308, DOI: https://dx.doi.org/10.21275/SR26704160308