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Comparative Study | Ophthalmology | Volume 15 Issue 6, June 2026 | Pages: 968 - 970 | India
Correlation of Central Corneal Thickness and Standard Deviation with Average Intraocular Pressure Variability in Primary Open-Angle Glaucoma: A Comparative Observational Study
Abstract: Background: Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness. Central corneal thickness (CCT) is a critical factor influencing intraocular pressure (IOP) measurements and glaucoma risk assessment. Standard deviation (SD) of IOP measurements reflects variability in tonometric recordings. Aim: To compare CCT and SD of IOP measurements between POAG patients and normal controls, and to evaluate their diagnostic utility. Results: Mean CCT in POAG patients was 509.44 ± 30.57 ?m compared to 557.82 ± 29.92 ?m in normals. Mean SD of IOP was 4.53 ± 1.73 dB in POAG vs. 3.83 ± 1.57 dB in normals. Mean IOP was 1.27 ± 1.97 mmHg in POAG vs. -0.90 ± 1.59 mmHg in normals. Conclusion: POAG patients exhibited significantly thinner CCT and higher SD variability compared to normal controls, supporting the role of CCT-adjusted IOP in glaucoma management.
Keywords: Primary open-angle glaucoma (POAG), central corneal thickness (CCT), intraocular pressure (IOP), standard deviation, tonometry, glaucoma screening
How to Cite?: Dr. Divya Bansal, Dr. Taran Wanage, Dr. Archana Tadwalkar, Dr. Jatin Karnani, "Correlation of Central Corneal Thickness and Standard Deviation with Average Intraocular Pressure Variability in Primary Open-Angle Glaucoma: A Comparative Observational Study", Volume 15 Issue 6, June 2026, International Journal of Science and Research (IJSR), Pages: 968-970, https://www.ijsr.net/getabstract.php?paperid=SR26615210651, DOI: https://dx.doi.org/10.21275/SR26615210651