Correlation Between Plasma D-Dimer Levels, Stroke Severity, and TOAST Classification in Patients with Acute Ischemic Stroke: A Cross-Sectional Analysis

Dr. Sushmasri Konidena, Dr. Muddarangappa R, Dr. Vineetha K. V

Abstract: Background: Acute ischemic stroke (AIS) is a major cause of morbidity and mortality, especially in developing countries. D-dimer, a marker of fibrin degradation, reflects thrombotic activity and may correlate with stroke severity and etiology. Objective: To assess the association of plasma D-dimer levels with stroke severity and etiological subtypes (TOAST classification) in AIS. Methods: This hospital-based cross-sectional study included 80 adults with imaging-confirmed AIS (March 2023?February 2025). Patients with conditions affecting coagulation were excluded. Stroke severity was assessed using NIHSS. Plasma D-dimer levels were measured within 72 hours. Etiology was classified by TOAST criteria. Statistical analysis was performed using SPSS, with p

Keywords: Acute ischemic stroke, D-dimer, NIHSS, TOAST classification, stroke severity

How to Cite?: Dr. Sushmasri Konidena, Dr. Muddarangappa R, Dr. Vineetha K. V, "Correlation Between Plasma D-Dimer Levels, Stroke Severity, and TOAST Classification in Patients with Acute Ischemic Stroke: A Cross-Sectional Analysis", Volume 15 Issue 6, June 2026, International Journal of Science and Research (IJSR), Pages: 873-877, https://www.ijsr.net/getabstract.php?paperid=SR26515131926, DOI: https://dx.doi.org/10.21275/SR26515131926

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