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Original Research | Obstetrics and Gynecology | Volume 15 Issue 5, May 2026 | Pages: 19 - 21 | India
Use of Carbetocin vs Oxytocin in Prevention of Postpartum Haemorrhage: A Comparative Study
Abstract: Background: Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide. Uterotonics such as oxytocin are routinely used for its prevention; however, carbetocin, a long-acting analogue, may offer improved efficacy. Aim: To compare the effectiveness of carbetocin and oxytocin in the prevention of postpartum hemorrhage. Methods: This prospective comparative study included 100 women undergoing vaginal delivery or cesarean section, randomly divided into two groups: Group A received carbetocin (100 μg IV) and Group B received oxytocin (10 IU IV infusion). Outcomes assessed included mean blood loss, need for additional uterotonics, hemoglobin drop, and incidence of PPH. Results: The mean blood loss was significantly lower in the carbetocin group compared to the oxytocin group (450 ± 120 mL vs 620 ± 150 mL). Requirement for additional uterotonics was reduced (10% vs 30%), as was the mean hemoglobin drop (0.9 ± 0.4 g/dL vs 1.5 ± 0.6 g/dL). The incidence of PPH was also lower in the carbetocin group (6% vs 18%). All differences were statistically significant (p
Keywords: Carbetocin, Oxytocin, Postpartum hemorrhage, Uterotonics, Maternal
How to Cite?: Dr. Sudhir Gupta, Dr. D. K. Gupta, Dr. Mohd Musheer Khan, "Use of Carbetocin vs Oxytocin in Prevention of Postpartum Haemorrhage: A Comparative Study", Volume 15 Issue 5, May 2026, International Journal of Science and Research (IJSR), Pages: 19-21, https://www.ijsr.net/getabstract.php?paperid=SR26427214249, DOI: https://dx.doi.org/10.21275/SR26427214249