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Original Article | Pathology | Volume 15 Issue 3, March 2026 | Pages: 1535 - 1538 | India
Comparative Study of Cytological Analysis of Thyroid Lesions According to Bethesda Classification and their Histopathological Correlation
Abstract: Introduction: Thyroid lesions are common occurrence in Indian population and represent widespread conditions usually benign but correct diagnosis is important crucially to ensure an appropriate treatment. Fine needle aspiration cytology (FNAC) has a crucial role in differentiating between neoplastic and non-neoplastic lesions. Bethesda classification helps in better understanding of the borderline cases where decision of surgical intervention over medical management is crucial. Aim: To classify the thyroid lesions according to Bethesda system and to corelate the results of cytological diagnosis with histological diagnosis. Materials and Methods: The present study was performed over a period of two years in department of pathology at tertiary care center. 100 cases of thyroid lesions were included in study which underwent FNAC and were classified according to Bethesda classification. Histopathological reports of the available cases were taken and corelated with cytological findings. Results: Of 100 cases, the most common category was Bethesda II (Benign)- 84 cases followed by category V (suspicious for malignancy) - 08 cases and category I (non-diagnostic)- 04 cases and least common were category III (02 cases) and suspicious for malignancy (02 cases). The cytological and histopathological diagnosis were corelated with each other in 50 cases among which 48 cases were concordant and 2 cases were discordant. Conclusion: FNAC is a simple and cost-effective diagnostic modality for detecting thyroid disease and has a good diagnostic accuracy with histopathology in detecting malignant thyroid lesions using the Bethesda system.
Keywords: Thyroid lesion, Cytology, Histopathology, Bethesda system
How to Cite?: Nimisha Tandon, Archana Bidari, C. P. Bhale, "Comparative Study of Cytological Analysis of Thyroid Lesions According to Bethesda Classification and their Histopathological Correlation", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 1535-1538, https://www.ijsr.net/getabstract.php?paperid=SR26325200851, DOI: https://dx.dx.doi.org/10.21275/SR26325200851