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Original Article | Pathology | Volume 15 Issue 3, March 2026 | Pages: 1419 - 1421 | India
Histopathological Spectrum of Upper Gastrointestinal Lesions in a Tertiary Care Centre of Gujarat: A Retrospective Cross-Sectional Analysis
Abstract: This comprehensive histopathological study of 91 upper gastrointestinal tract (GIT) biopsy specimens received at a tertiary care centre highlights a wide spectrum of both non-malignant, benign and malignant lesions, spanning various age groups. Aim: Histopathological evaluation of upper gastrointestinal lesions among patients treated at a tertiary care centre in Gujarat. Method: Retrospective observational study of total 91 upper gastrointestinal biopsies was conducted at Histopathology laboratory, Department of Pathology from January 2022 to December 2023. Result: Most esophageal lesions (83.78%) are malignant, predominantly squamous cell carcinoma, while Barrett?s esophagus and inflammatory lesions account for a small fraction. In the stomach and duodenum, the majority of lesions are nonneoplastic inflammatory conditions (gastritis and duodenitis), with very few gastric malignant cases (each 2%). Middle-aged males were most commonly affected, with a notable association between lesion type and gender. Conclusion: The findings emphasize the importance of early diagnosis and improved clinical management to reduce disease progression and overall GI-related health burden.
Keywords: Upper GIT, Esophagus, stomach, duodenum, malignancy, squamous cell carcinoma
How to Cite?: Dr. Srushti Chauhan, Dr. Jignasha Patel, Dr. Jignasha Bhambhaniya, "Histopathological Spectrum of Upper Gastrointestinal Lesions in a Tertiary Care Centre of Gujarat: A Retrospective Cross-Sectional Analysis", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 1419-1421, https://www.ijsr.net/getabstract.php?paperid=SR26323140617, DOI: https://dx.doi.org/10.21275/SR26323140617