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Original Article | Biomedical Sciences | Volume 15 Issue 3, March 2026 | Pages: 1290 - 1292 | India
Study of Serum Iron Profile in Type 2 Diabetes Mellitus Patients in a Tertiary Care Hospital in Ghaziabad
Abstract: Background: Type 2 Diabetes Mellitus (T2DM) is a major metabolic disorder associated with dysregulated iron metabolism. This study aimed to evaluate and compare the serum iron profile in T2DM patients and healthy controls. Methods: A case-control study was conducted on 140 participants (70 T2DM patients and 70 controls). Serum iron, ferritin, total iron-binding capacity (TIBC), unsaturated iron-binding capacity (UIBC), fasting blood sugar (FBS), and HbA1c were estimated. Data were analyzed using SPSS v27, with p<0.05 considered statistically significant. Results: T2DM patients had significantly higher serum iron (187.0±8.2 μg/dL vs 102.1±23.3 μg/dL) and ferritin (428.7±15.1 ng/mL vs 98.8±12.4 ng/mL) compared to controls (p<0.001). TIBC and UIBC were also elevated. BMI and glycemic indices were significantly higher in diabetics. HbA1c positively correlated with serum iron (r=0.62, p<0.001). Conclusion: Elevated serum iron and ferritin levels in T2DM patients suggest a link between iron overload and poor glycemic control. Monitoring iron metabolism may help prevent diabetes-related complications.
Keywords: Type 2 Diabetes Mellitus, Serum Iron, Ferritin, TIBC, UIBC, Glycemic Control
How to Cite?: Dr. Nitin Patrick, Dr. Juhi Aggarwal, Urvashi Midha, "Study of Serum Iron Profile in Type 2 Diabetes Mellitus Patients in a Tertiary Care Hospital in Ghaziabad", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 1290-1292, https://www.ijsr.net/getabstract.php?paperid=SR26321110934, DOI: https://dx.dx.doi.org/10.21275/SR26321110934