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Research Paper | Zoology | Volume 15 Issue 3, March 2026 | Pages: 1235 - 1238 | India
Toxicological Effects of Dimethoate (Rogor 30 %EC) on Ovary of Female Rat Rattus Rattus Norvigicus
Abstract: Dimethoate is a widely used organophosphorus (OP) insecticide applied to kill mites and insects systemically and on contact. The toxicological effect of dimethoate on ovary of female rat which total 90 animals were divided into 3 groups of 30 each; each group were further divided in to three sub groups for 15 30 and 60 days. The first group was served as a control administered with daily dose of vehicle olive oil orally by the help of cannula; the second and third group was exposed with daily dose of dimethoate (rogor 30 % EC) dissolved in olive oil by the help of cannula. In the result we find that in the histopathological changes ovary in the rats females were treated with dimethoate. The initial morphological changes in the ovary following decided dose of dimethoate include reduced size of graffian follicles. The stromal cells and ovarian follicles become degenerated condition after exposure of dimethoate upto 15 days as compared to control and supplemented groups. After 30 days dimethoate exposure showed reduced gross size of ovarian follicles and in the follicles were some atrophic and degenerative changes in ovarian follicles with reduced oocytes. The interstitial tissue is also in atrophied condition and corpus luteum is hypertrophied and as compared to the control 15 days and olive oil supplements treated groups. dimethoate acts by interfering with the activities of cholinesterase, an enzyme essential for the proper functioning of the nervous system of insects and humans.
Keywords: Dimethoate toxicity, ovarian damage olive oil, organophosphorus insecticide histopathological changes acetylecholineestrase
How to Cite?: Dr. Gabbar Singh Lodhi, "Toxicological Effects of Dimethoate (Rogor 30 %EC) on Ovary of Female Rat Rattus Rattus Norvigicus", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 1235-1238, https://www.ijsr.net/getabstract.php?paperid=SR26320135028, DOI: https://dx.dx.doi.org/10.21275/SR26320135028