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Original Article | Radiotherapy and Oncology | Volume 15 Issue 3, March 2026 | Pages: 875 - 878 | India
Local Control and Toxicity Outcomes Following IMRT or VMAT in Postoperative Benign Brain Tumors: A Single Institution Retrospective Study
Abstract: Introduction: Benign brain tumors such as meningiomas, pituitary adenomas, craniopharyngiomas, and schwannomas, though histologically non-malignant, may be life-threatening due to their critical intracranial location. Modern radiotherapy techniques, including Intensity-Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT), allow high-precision treatment while sparing adjacent structures. Aims and Objectives: The primary aim was to evaluate tumor response and local control one year after radiotherapy. Secondary objectives included assessing radiation-induced toxicities and correlating outcomes with histological subtypes. Materials and Methods: A retrospective study was conducted at Medical College Kolkata between January 2023 and August 2024. Thirty patients with histologically confirmed benign brain tumors were enrolled post-surgery and treated with IMRT or VMAT. Doses ranged between 50.4 and 54 Gy in 1.8 Gy per fraction. Patients were followed every three months for one year. Tumor response was assessed radiologically, and toxicities graded using CTCAE v5.0. Statistical analysis included Chi-square testing, with p_value
Keywords: meningiomas, pituitary adenomas, craniopharyngiomas, schwannomas, IMRT, VMAT
How to Cite?: Dr. Subhrajyoti Sengupta, Dr. Shinjini Chakrabarty, Dr. Soumish Sengupta, "Local Control and Toxicity Outcomes Following IMRT or VMAT in Postoperative Benign Brain Tumors: A Single Institution Retrospective Study", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 875-878, https://www.ijsr.net/getabstract.php?paperid=SR26314192937, DOI: https://dx.doi.org/10.21275/SR26314192937