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Original Article | Obstetrics and Gynecology | Volume 15 Issue 3, March 2026 | Pages: 1276 - 1278 | India
Ovarian Mixed Germ Cell Tumour with Choriocarcinomatous Component Mimicking Ectopic Pregnancy
Abstract: Background: Ovarian germ cell tumors constitute a small proportion of ovarian malignancies but predominantly affect adolescents and young women. Mixed germ cell tumors containing choriocarcinomatous elements are particularly rare and may present with elevated beta-human chorionic gonadotropin (?-hCG) levels, thereby mimicking pregnancy-related conditions such as ectopic pregnancy. Case description: We report the case of a 16-year-old adolescent girl who presented with acute abdominal pain, vomiting, syncope, and a background of chronic generalized weakness. Clinical evaluation revealed anemia, dehydration, and signs of acute abdomen. A positive urine pregnancy test with ultrasonographic findings suggestive of a ruptured right adnexal ectopic pregnancy led to an initial provisional diagnosis of a ruptured tubo-ovarian mass. Emergency diagnostic laparoscopy revealed a ruptured right tubo-ovarian mass with massive hemoperitoneum (1300 mL). Right salpingo-oophorectomy was performed. Histopathological examination and immunohistochemistry confirmed a mixed germ cell tumor of the right ovary comprising dysgerminoma with choriocarcinoma. Conclusion: This case highlights the diagnostic dilemma posed by germ cell tumors mimicking ectopic pregnancy in adolescents and underscores the importance of histopathological evaluation in acute gynecological emergencies.
Keywords: Mixed germ cell tumor, ovary, dysgerminoma, choriocarcinoma, adolescent, acute abdomen, hemoperitoneum
How to Cite?: Dr. Supriya Kottapalli, Dr. Aparna Nair, Dr. Harshitha M, Dr. C P Srujana, "Ovarian Mixed Germ Cell Tumour with Choriocarcinomatous Component Mimicking Ectopic Pregnancy", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 1276-1278, https://www.ijsr.net/getabstract.php?paperid=SR26311213613, DOI: https://dx.doi.org/10.21275/SR26311213613