Surgical Management of Massive Splenomegaly and Life-Threatening Hypersplenism in a Young Female with Decompensated Liver Cirrhosis

Dr. Karan Lalsingbhai Muniya, Dr. J. G. Vagadia

Abstract: This case report discusses a 25-year-old female (G3P3L3) presenting with melena, abdominal pain, and massive splenomegaly (26 cm). Investigations revealed liver cirrhosis with clinically significant portal hypertension, Grade 3 oesophageal varices, GAVE, and profound pancytopenia. Despite high indirect bilirubin (8.08 mg/dL) and Child-Pugh Class B status, the patient underwent successful splenectomy after vaccination. Post-operative results showed immediate reversal of hypersplenism and stabilisation of liver markers. This case highlights the role of splenectomy in correcting hematological profiles in cirrhotic patients to improve quality of life and reduce variceal pressure.

Keywords: Splenectomy, Hypersplenism, Portal Hypertension, GAVE, Liver Cirrhosis

How to Cite?: Dr. Karan Lalsingbhai Muniya, Dr. J. G. Vagadia, "Surgical Management of Massive Splenomegaly and Life-Threatening Hypersplenism in a Young Female with Decompensated Liver Cirrhosis", Volume 15 Issue 1, January 2026, International Journal of Science and Research (IJSR), Pages: 1825-1826, https://www.ijsr.net/getabstract.php?paperid=SR26131112153, DOI: https://dx.doi.org/10.21275/SR26131112153