Rhino-Orbital Mucormycosis with Secondary Cutaneous Facial Necrosis: A Rare ENT-Dermatology Correlated Case

Dr. Pooja Saroj, Dr. Ankush Babal

Abstract: Rhino-orbital mucormycosis is an aggressive, angioinvasive fungal infection predominantly affecting immunocompromised individuals, especially those with uncontrolled diabetes mellitus and recent corticosteroid use. Secondary cutaneous facial involvement is rare and indicates advanced disease with increased morbidity and mortality. We report a rare case of rhino-orbital mucormycosis in a 54-year-old diabetic male with a recent history of COVID-19 associated steroid therapy. The patient presented to the ENT outpatient department with unilateral facial pain, nasal obstruction, and blood-tinged nasal discharge. Endoscopic examination revealed necrotic nasal mucosa, and microbiological evaluation confirmed mucormycosis. Despite early diagnosis and initiation of antifungal therapy, the patient developed rapidly progressive secondary cutaneous facial necrosis over the left malar region. Histopathology of skin biopsy demonstrated angioinvasive, aseptate fungal hyphae, confirming secondary cutaneous mucormycosis. Management involved aggressive multidisciplinary care with intravenous liposomal amphotericin B, strict glycaemic control, repeated endoscopic sinus debridement, and surgical excision of necrotic facial skin. Secondary cutaneous facial necrosis in rhino-orbital mucormycosis represents severe disease progression. Early recognition, prompt antifungal therapy, radical surgical debridement, and close ENT?Dermatology collaboration are crucial to improving survival and clinical outcomes.

Keywords: Mucormycosis, Rhino-orbital mucormycosis, Cutaneous facial necrosis, Black eschar, Invasive fungal sinusitis, ENT?Dermatology interface

How to Cite?: Dr. Pooja Saroj, Dr. Ankush Babal, "Rhino-Orbital Mucormycosis with Secondary Cutaneous Facial Necrosis: A Rare ENT-Dermatology Correlated Case", Volume 15 Issue 1, January 2026, International Journal of Science and Research (IJSR), Pages: 163-164, https://www.ijsr.net/getabstract.php?paperid=SR26104175416, DOI: https://dx.doi.org/10.21275/SR26104175416