Psychophysiological Mechanisms of Stress Impact on Hair Loss Processes

Anna Dieriahina

Abstract: The article presents a theoretical and analytical review of current data on the neuroendocrine, neurogenic, molecular, and cellular mechanisms of stress-induced hair loss and their practical significance for the hairdressing industry. The study is based on an interdisciplinary approach combining dermatology, trichology, neurobiology, and psychophysiology, allowing stress to be viewed as a complex factor acting through hormonal cascades, neural regulation, microinflammation, and oxidative damage to follicular cells. Particular attention is paid to the analysis of pathogenetic links, including the influence of CRH, ACTH, substance P, norepinephrine, cortisol, and sympathetic nervous system responses, as well as the role of DNA damage and pigmentation disorders in altering hair growth cycles. Therapeutic intervention points already used in medicine (NK-1R inhibitors, JAK inhibitors, antioxidants, local norepinephrine administration) are presented, and possibilities for their integration with aesthetic care methods are outlined. It is shown that a hairdresser-stylist, possessing knowledge of the pathogenesis of stress-induced alopecia, can act as the first link in the prevention system, ensuring early detection of pathological signs, informing clients about possible medical approaches, and facilitating collaboration with physicians. The article will be useful to professionals in hairdressing, trichology, dermatology, and researchers studying the psychophysiological aspects of hair health.

Keywords: stress-induced alopecia, neuroendocrine regulation, substance P, cortisol, norepinephrine, oxidative stress, hair loss, therapeutic interventions, hairdressing, trichology

How to Cite?: Anna Dieriahina, "Psychophysiological Mechanisms of Stress Impact on Hair Loss Processes", Volume 14 Issue 9, September 2025, International Journal of Science and Research (IJSR), Pages: 302-305, https://www.ijsr.net/getabstract.php?paperid=SR25906181534, DOI: https://dx.doi.org/10.21275/SR25906181534