Study the Level of IL-6 in Vitiligo Patients Having Progression After Being COVID Positive within One Month and Compare it to the Level of Patients Who Have Progression with COVID Negative

Dr. Shweta Mathur, Dr. Dilip Kachhawa, Dr. Pankaj Rao

Abstract: Background: Vitiligo is a common, acquired, discoloration of the skin, characterized by well circumscribed, ivory or chalky white macules. Etio-pathogenesis of vitiligo is multifactorial and polygenic consisting of genetic, immunological and environmental factors. During the recent pandemic of Covid-19 it was observed that Vitiligo in patients aggravated possibly because there is cytokine storm in covid patients mainly of interleukin-6. Aims and objective: To find out the level of IL6 in a known patient of vitiligo with history of aggravation and seropositive for covid -19. To find out the level of IL 6 in known patient of vitiligo with history of aggravation during covid 19 but serologically negative. Material and Methodology: Hospital based observational study. Inclusion criteria patients with progressive vitiligo after being Covid positive in a month and patient with progressive vitiligo who are Covid negative and patients aging 18-65. Discussion: Analysis was conducted using t-test for continuous variables demonstrating clear correlation between IL-6 elevation and COVID-19 positivity in vitiligo patients. This data supports the hypothesis that COVID-19 may influence autoimmune conditions like vitiligo through inflammatory pathways involving IL-6.

Keywords: Vitiligo, IL-6, COVID-19, autoimmune disease, cytokines, inflammation

How to Cite?: Dr. Shweta Mathur, Dr. Dilip Kachhawa, Dr. Pankaj Rao, "Study the Level of IL-6 in Vitiligo Patients Having Progression After Being COVID Positive within One Month and Compare it to the Level of Patients Who Have Progression with COVID Negative", Volume 14 Issue 7, July 2025, International Journal of Science and Research (IJSR), Pages: 1512-1513, https://www.ijsr.net/getabstract.php?paperid=SR25708233405, DOI: https://dx.doi.org/10.21275/SR25708233405