Health- Related Quality-of-Life in Rheumatoid Arthritis Assessed by Short-Form 36 and its Relation to Disease Activity

Kottu Lakshmi Tejaswi, Rajeswari S., Balaji C., Nidhi Ramesh Prabhu, Akanksha S., Tejas M., Tarik, Vishali

Abstract: Background: Rheumatoid arthritis (RA) impacts both physical and mental well-being, with health-related quality of life (HRQoL) often prioritized by patients over laboratory or clinical parameters. Poor QoL is associated with increased healthcare utilization. Objective: To assess HRQoL in RA patients and its correlation with disease activity. Methods: This cross-sectional study was conducted at SRIHER, Chennai, from March to June 2024. RA patients fulfilling ACR/EULAR 2010 criteria were included. HRQoL was measured using the SF-36 questionnaire, assessing eight domains and two summary scores?Physical Component Summary (PCS) and Mental Component Summary (MCS). Disease activity was measured using DAS28-ESR. Results: Among 100 patients (86% female, mean age 51.9 ? 11.3 years), 54% had RA >5 years. Mean DAS28 was 3.4 ? 1.3. Females had significantly lower PCS and MCS scores. Longer disease duration correlated with lower HRQoL. DAS28 showed a strong negative correlation with PCS (r = -0.791) and MCS (r = -0.620), both p

Keywords: Rheumatoid Arthritis, Health-Related Quality of Life (HRQoL), SF-36 Questionnaire, DAS28-ESR, Disease Activity

How to Cite?: Kottu Lakshmi Tejaswi, Rajeswari S., Balaji C., Nidhi Ramesh Prabhu, Akanksha S., Tejas M., Tarik, Vishali, "Health- Related Quality-of-Life in Rheumatoid Arthritis Assessed by Short-Form 36 and its Relation to Disease Activity", Volume 14 Issue 4, April 2025, International Journal of Science and Research (IJSR), Pages: 828-831, https://www.ijsr.net/getabstract.php?paperid=SR25407223406, DOI: https://dx.doi.org/10.21275/SR25407223406

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