Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC): A Mental and Physical Agony in a Young: A Case Report

Dr. Kunmun Sahu, Dr. R. N. Behera

Abstract: Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC) is a rare autosomal dominant disorder characterised by multiple cutaneous and uterine leiomyomas, with an increased risk of developing aggressive renal cell carcinoma. This case study presents a 28yr old woman from a low socioeconomic background with a history of heavy menstrual bleeding, multiple fibroids, and infertility, leading to a total abdominal hysterectomy after unsuccessful myomectomy. A strong family history of fibroids was noted, with her mother and sisters experiencing similar conditions. Postoperatively, dermatological examination confirmed piloleiomyoma, and nephrological evaluation revealed early - stage renal cell carcinoma. This case highlights the importance of early diagnosis through clinical evaluation, pedigree analysis, and serial imaging. Increased awareness, genetic counselling, and further research are essential to improve patient outcomes and early detection of HLRCC.

Keywords: HLRCC, uterine leiomyoma, renal cell carcinoma, piloleiomyoma, FH, genetic counselling, early diagnosis

How to Cite?: Dr. Kunmun Sahu, Dr. R. N. Behera, "Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC): A Mental and Physical Agony in a Young: A Case Report", Volume 14 Issue 2, February 2025, International Journal of Science and Research (IJSR), Pages: 712-713, https://www.ijsr.net/getabstract.php?paperid=SR25207192859, DOI: https://dx.doi.org/10.21275/SR25207192859