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Research Paper | Health and Medical Sciences | India | Volume 14 Issue 2, February 2025 | Popularity: 5.6 / 10
CT Severity Index Score and Serum Procalcitonin Level: A Prospective Study for Early Assessment of Severity and Prognosis in Acute Pancreatitis
Dr. Debashis Nanda, Dr. Biranchi Narayan Lenka, Dr. Prajit Nayak, Dr. Manas Pandey
Abstract: Background: Acute pancreatitis (AP) ranges from a mild, self - limiting condition to severe acute pancreatitis (SAP) with complications like organ failure and pancreatic necrosis, necessitating early risk stratification for better clinical management. This study evaluates the prognostic value of the Modified Computed Tomography Severity Index (CTSI) score and serum procalcitonin levels in predicting AP severity, organ failure, and clinical outcomes such as ICU admission, length of hospital stay, and mortality. Methodology: The study is a prospective observational study conducted at Hi - Tech Medical College & Hospital, Bhubaneswar from March 2023 to January 2025, involving all patients diagnosed with acute pancreatitis in the Department of General Surgery. Patients meeting the inclusion criteria were enrolled using purposive sampling, and their demographic, clinical, and laboratory data were recorded. Diagnosis was based on clinical presentation, elevated serum enzyme markers, and imaging findings, with further evaluation of CTSI score and serum procalcitonin levels for prognostic assessment. Result & Conclusion: 80 Patients were included in my study with 48 males and 32 females, of which most of the patients were of the 4th decade followed by 6th and 7th decade.21 % of the study population who developed Acute Pancreatitis consumed alcohol, 48% of the study population developed components of SIRS on admission and at 48 hours after admission, 68% of the study population had elevated Serum Procalcitonin level & 10 Patients out of the study group of 80 died during the period of hospitalisation. Serum procalcitonin (PCT) levels at admission do not reliably predict progression to severe acute pancreatitis but may help identify disease severity and guide antibiotic therapy duration.
Keywords: Acute Pancreatitis, Serum Procalcitonin (PCT), CTSI Score, Pancreatic Necrosis, Acute oedematous pancreatitis, Acute necrotising pancreatitis, BISAP scoring, RANSON scoring, BALTHAZAR scoring, APACHE II
Edition: Volume 14 Issue 2, February 2025
Pages: 311 - 313
DOI: https://www.doi.org/10.21275/SR25204190025
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