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Research Paper | Cardiology Science | Volume 14 Issue 10, October 2025 | Pages: 461 - 465 | India
Association of High-Sensitivity C-Reactive Protein with Cardiovascular Risk Factors, Clinical Features, and Angiographic Findings in Young Adults with Acute Coronary Syndrome: An Analytical Cross-Sectional Study
Abstract: Background: Acute coronary syndrome (ACS) among young adults (?45 years) is an emerging public health concern, with premature events leading to significant morbidity, mortality, and socioeconomic burden. Inflammation is central to atherosclerosis and plaque instability, with high-sensitivity C-reactive protein (hs-CRP) serving as a reliable biomarker of cardiovascular risk. However, its role in relation to angiographic profile and risk factors in younger ACS patients remains underexplored. Methods: This hospital-based analytical cross-sectional study enrolled 239 consecutive ACS patients aged 3 mg/l. Coronary angiography was performed in eligible patients and categorized as single-vessel disease (SVD), double-vessel disease (DVD), or triple-vessel disease (TVD). Associations between hs-CRP, clinical presentation, and angiographic severity were analysed. Results: Elevated hs-CRP (>3 mg/l) was observed in 56.9% of patients and showed significant associations with smoking, metabolic syndrome, central obesity, periodontitis, dyslipidaemia, and premature coronary artery disease (p
Keywords: Acute coronary syndrome, young adults, high-sensitivity C-reactive protein, cardiovascular risk factors, coronary angiography, inflammation
How to Cite?: Dr. Dheeraj Karde, Dr. Sunil Washimkar, Dr. Atulsingh Rajput, Dr. Sharada Bholay, "Association of High-Sensitivity C-Reactive Protein with Cardiovascular Risk Factors, Clinical Features, and Angiographic Findings in Young Adults with Acute Coronary Syndrome: An Analytical Cross-Sectional Study", Volume 14 Issue 10, October 2025, International Journal of Science and Research (IJSR), Pages: 461-465, https://www.ijsr.net/getabstract.php?paperid=SR251001054612, DOI: https://dx.doi.org/10.21275/SR251001054612