Papillon - Lefevre Syndrome: A Rare Case Report
Abstract: Papillon - Lefevre syndrome is a rare condition, inherited through autosomal recessive inheritance, defined by hyperkeratosis of the palms and soles and severe, early - onset destructive periodontitis that results in the premature loss of both primary and permanent teeth. This syndrome is linked to mutations in the cathepsin C gene, located in the main gene locus of chromosome 11q14. Early diagnosis and intervention can help preserve the patient?s teeth and delay premature loss. This case study discusses a 6 - year - old Saudi girl who displays all the characteristic features of Papillon - Lefevre syndrome.
Keywords: Papillon - Lefevre syndrome, hyperkeratosis, periodontitis, cathepsin c gene
How to Cite?: Abdullah Al Saleh, "Papillon - Lefevre Syndrome: A Rare Case Report", Volume 13 Issue 7, July 2024, International Journal of Science and Research (IJSR), Pages: 511-512, https://www.ijsr.net/getabstract.php?paperid=SR24708033120, DOI: https://dx.doi.org/10.21275/SR24708033120