Papillon - Lefevre Syndrome: A Rare Case Report
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Case Studies | Medical Science | Saudi Arabia | Volume 13 Issue 7, July 2024 | Popularity: 5 / 10


     

Papillon - Lefevre Syndrome: A Rare Case Report

Abdullah Al Saleh


Abstract: Papillon - Lefevre syndrome is a rare condition, inherited through autosomal recessive inheritance, defined by hyperkeratosis of the palms and soles and severe, early - onset destructive periodontitis that results in the premature loss of both primary and permanent teeth. This syndrome is linked to mutations in the cathepsin C gene, located in the main gene locus of chromosome 11q14. Early diagnosis and intervention can help preserve the patient?s teeth and delay premature loss. This case study discusses a 6 - year - old Saudi girl who displays all the characteristic features of Papillon - Lefevre syndrome.


Keywords: Papillon - Lefevre syndrome, hyperkeratosis, periodontitis, cathepsin c gene


Edition: Volume 13 Issue 7, July 2024


Pages: 511 - 512


DOI: https://www.doi.org/10.21275/SR24708033120


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Abdullah Al Saleh, "Papillon - Lefevre Syndrome: A Rare Case Report", International Journal of Science and Research (IJSR), Volume 13 Issue 7, July 2024, pp. 511-512, https://www.ijsr.net/getabstract.php?paperid=SR24708033120, DOI: https://www.doi.org/10.21275/SR24708033120

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