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Research Paper | Pharmacology Science | India | Volume 13 Issue 4, April 2024

Study of Chronopharmacology and Drug Prescribing Pattern in Tertiary Care Hospital

Dr. Dipal H. Vaishnav | Dr. Jayesh D. Balat | Dr. Hiren R. Trivedi

Abstract: Introduction: Chronopharmacology is the science dealing with the optimization of drug effects and the minimization of adverse effects by timing medication in relation to the biological rhythm. In the treatment of several illnesses, including allergies and cardiovascular conditions, this chronopharmacological concept is applied. The study aimed to examine the application of the chronopharmacological approach in clinical practice by comparing the chronopharmacology of six medications with the physician?s prescribing patterns. Methodology: This study was prospective and observational conducted by Department of Pharmacology in association with department of medicine and respiratory medicine at tertiary care teaching hospital over a period of 6 months from April to September 2023. Total 180 prescriptions were audited. Six commonly used drugs such as Beta blockers, ACE inhibitor, Insulin, Statins, Theophylline and Proton pump inhibitors were used. Result: Following is the chronopharmacological data of prescription as observed: Theophylline and statins have maximum matching pattern 100%, followed by ACE inhibitor and Beta blockers (96.66%), insulin (86.66%) and PPI (66.66%). Conclusion: The chronotherapeutic approach provides a more accurate determination of the time when patients are most at risk and require the most therapy. Patients may benefit from higher therapeutic effectiveness and fewer side effects if medications are given using a chronopharmacological approach.

Keywords: Chronopharmacolgy, Prescribing pattern, side effects

Edition: Volume 13 Issue 4, April 2024,

Pages: 890 - 893