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Review Papers | Pharmacy | India | Volume 13 Issue 3, March 2024

Unravelling the Potential of Curcumin in Cancer Treatment: A Comprehensive Exploration

Anjana Vidya Srivathsa | Harish Kumar DR | Hareesh Kumar P

Abstract: The potential use of curcumin, a naturally occurring substance produced from turmeric, as a medicinal agent in the treatment of cancer is examined in this study. New treatment strategies are essential since cancer is a worldwide health concern. High incidence and death rates for cancer still exist despite advances in therapy, especially in lower - and middle - income nations. Because side effects frequently make traditional cancer therapy unworkable, experts are looking for other approaches. In addition, this research explores the chemistry of curcumin, emphasizing its spectral properties, solubility, and structure. Although its safety profile has been established, problems such as low solubility in water still exist. To improve efficacy, techniques such encapsulation in nano - formulations and structural alteration are investigated. More than 160 clinical trials demonstrate the increasing interest in the therapeutic effects of curcumin, especially in the treatment of cancer. Furthermore, this study investigates the chemistry of curcumin, focusing on its structure, solubility, and spectral characteristics. Despite having a well - established safety profile, it nevertheless has issues including limited water solubility. Techniques including structural modification and encapsulation in Nano formulations are being researched to increase effectiveness. The growing interest in curcumin's therapeutic properties, particularly in the treatment of cancer, is reflected in the more than 160 clinical studies that have been conducted.

Keywords: Cancer, heterocyclic curcumin derivative, cell line study, anti - proliferative

Edition: Volume 13 Issue 3, March 2024,

Pages: 1278 - 1285