Pseudomonas Aeruginosa Prevalence, Antibiotic Resistance and Antimicrobial use in Burn Wards from Nagpur City of Maharashtra

Dr Milan Nimbalkar

Abstract: To assess the application of antibacterial agents, alongside pathogen, prevalence and Pseudomonas aeruginosa drug resistance, with the aim of understanding the impact of inappropriate antibacterial use. This retrospective study assessed bacteria from wounds, catheters, blood, faeces, urine and sputum of hospitalized patients in burn wards between June 2018 to December 2018. The intensity of use of antibacterial agents and resistance of P. aeruginosa to common anti - Gram - negative antibiotics were measured. Annual detection rates of Staphylococcus aureus were significantly decreased, whereas annual detection rates of P. aeruginosa and Klebsiella pneumoniae were significantly increased. Multidrug - resistant strains of P. aeruginosa were increased. The intensity of use of some anti - Gram negative antibiotics positively correlated with resistance rates of P. aeruginosa to similar antimicrobials. In burn wards, more attention should be paid to P. aeruginosa and K. pneumoniae. The use of ciprofloxacin, ceftazidime and cefoperazone/ sulbactam should be limited to counter the related increase in resistance levels.

Keywords: antibacterial resistance, Pseudomonas aeruginosa, burn wards, drug usage, multidrug-resistant