Analyzing Left Ventricular Mass Across Weight and Metabolic Health Categories: Insights from an Observational Study

Dr. Sweta Patel, Dr. Ramanand Sinha

Abstract: Background: Left ventricular (LV) hypertrophy is an established independent cardiovascular risk factor. LV mass is influenced by multiple factors such as race, ethnicity, gender, and the degree of central and peripheral adiposity. This study aims to analyse LV mass via transthoracic echocardiography in individuals with varying weight categories (normal weight, pre-obese, and obese) and metabolic health statuses (metabolically healthy/unhealthy). Methods: An observational study was conducted among 120 patients at Mahatma Gandhi medical college and hospital. Participants were categorized based on their body mass index (BMI) into normal weight, pre-obese, and obese groups. Metabolic health status was assessed, and LV mass was measured using transthoracic echocardiography. Clinical, anthropometric, and biochemical parameters were collected and analysed. Results: Normal weight patients were predominantly aged 61-70 years, while obesity and pre-obesity were most common in the 41-51 years age group. A significant association was found between LV mass and BMI. LV mass in metabolically healthy normal weight, pre-obese, and obese patients were 140.8 ? 20.2, 143.1 ? 25.5, and 159.8 ? 31.1 respectively. Metabolically unhealthy counterparts had LV masses of 154.4 ? 21.2, 178.6 ? 29.4, and 181.45 ? 45.0 respectively. LV mass index showed a significant association with waist circumference and other parameters including age, total cholesterol, triglycerides, HDL, LDL, and hypertension. Conclusion: Metabolic health significantly influences LV mass across all BMI categories. Obesity impacts LV mass independently of metabolic syndrome components, indicating that metabolically healthy obese individuals exhibit subclinical adverse changes in LV mass. Waist circumference is a more accurate predictor of LV mass index than BMI.

Keywords: Metabolically healthy, metabolically unhealthy, LV mass, obesity, cardiovascular risk

How to Cite?: Dr. Sweta Patel, Dr. Ramanand Sinha, "Analyzing Left Ventricular Mass Across Weight and Metabolic Health Categories: Insights from an Observational Study", Volume 13 Issue 12, December 2024, International Journal of Science and Research (IJSR), Pages: 173-178, https://www.ijsr.net/getabstract.php?paperid=SR241201130920, DOI: https://dx.doi.org/10.21275/SR241201130920