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Experimental Result Paper | Ayurveda | India | Volume 13 Issue 1, January 2024 | Rating: 5.7 / 10
An Experimental Study to Evaluate Antidiarrheal Activity and Antimicrobial Activity of Ananda Rasa
Dr. Chaitra L V
Abstract: Ananda rasa is a Khalveeya Rasaoushadi mentioned in Vaidya Chintamani, indicated in Atisara and contains Hingula, Saindhava, Varatika, Vatsanabha, Pippali, Sunti, Jatiphala and Dhattura Beeja. In present era people believe in proved facts and require rationality behind facts. Hence the facts have to be proved by scientific methods and establish the facts through experimental trail. So in the present study, Animal experimentation was chosen to validate scientifically that Ananda Rasa is effective in Atisara through Anti - diarrheal activity models. Objective: To evaluate antidiarrheal and antimicrobial property of Ananda Rasa. Methods: Experimental study was conducted for acute toxicity on 5 rats and antidiarrheal study in 4 groups - Control, Standard, Test (175mg), Test (2000mg) each group contains 6 rats. Antidiarrheal study was done by Castor oil induced diarrhea, Castor oil induced enteropooling and Gastro intestinal motility to evaluate latency, frequency, enteropooling and intestinal motility. Antimicrobial study was conducted on Staphylococusaures and E. coli. Result: Ananda Rasa was found safe even at high dose. Ananda Rasa shown efficacy in reducing latency, frequency, intestinal motility andintestinal secretion compared to standard and control group. Ananda Rasa showed significant Zone of inhibition for Staphylococusaures and E coli. Results were statistically significant. Conclusion: Ananda Rasa possess significant antidiarrheal activity in inhibition of diarrhea, intestinal secretion, intestinal motility and possess significant antimicrobial activity.
Keywords: Ananda Rasa, castor oil induced enteropooling, intestinal motility, antidiarrheal activity, antimicrobial, acute toxicity activity
Edition: Volume 13 Issue 1, January 2024,
Pages: 977 - 981