Clinical and Hematological Evaluation of Bicytopenia: A Cross-Sectional Study

Dr. Nalajala Rushi Kiran, Dr. Adithi KMD

Abstract: This study focuses on the clinical and hematological profile of patients diagnosed with bicytopenia, a condition characterized by a decrease in red blood cells and platelets. A cross-sectional observational study was conducted at the General Medicine Department of K S Hegde Medical Academy, evaluating 60 patients from August 2022 to September 2023. Fever, anemia, and bleeding tendencies were the most common clinical presentations. The majority of cases were attributed to hypersplenism, followed by megaloblastic anemia. Peripheral blood smears and bone marrow examinations were performed when necessary to determine the underlying causes. The findings suggest that hypersplenism is the leading cause of bicytopenia, particularly in younger patients, with a significant proportion showing Vitamin B12 deficiency.

Keywords: Bicytopenia, hypersplenism, megaloblastic anemia, cross-sectional study, hematological