International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Chemistry | Indonesia | Volume 12 Issue 9, September 2023


Antibacterial and Antioxidant Activity of Trigona Sp Nanopropolis

Ida Ayu Gede Widihati [2] | Ni Gusti Ayu Dwi Adhi Suastuti | Shirly Aulia Rahma | Ni Made Puspawati


Abstract: Propolis is one of the important by-products of bees used as a component of the body's defense, external immune system and antimicrobial. Trigona Sp bees are a type of bee native to Asia that has the characteristic that the honey produced has a sour taste but is resistant to fermentation and rarely moves, and the haractivity of its honey products is higher than that of Apis genus honey. In this study, particle size modification of propolis from Trigona Sp spider honey into nano-sized particles was carried out using the ionic gelation method. The resulting nanopropolis was tested for antioxidant activity using the DPPH shift method and tested for antibacterial activity against Staphylococcus Aureus bacteria. Through phytochemical tests, it was found that propolis was positive for tannins, flavonoids, and alkaloids, but negative for saponins. Antioxidant activity test showed that nanopropolis had weak antioxidant activity (500-650 mg/L) while propolis in bulk form had very weak antioxidant activity (2092.2 mg/L). The inhibition against Staphylococcus Aureus bacteria of propolis extract, NP1:5, NP1;10, and NP 1:15 were 0 mm, 18 mm, 12 mm, and 8 mm, respectively.


Keywords: Propolis, Trigona Sp bees, nanopropolis, antioxidant activity, antibacterial activity


Edition: Volume 12 Issue 9, September 2023,


Pages: 1934 - 1937


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