Kounis Syndrome: Unveiling Allergic Triggers for Acute Coronary Events - A Case Study of Contrast Dye Induced Reaction during Percutaneous Coronary Intervention

Tanae EL GHALI, Najlae Belharty, Zakaria Choho, Fatima Azzahra Benmessaoud, Latifa Oukerraj, Mohamed Cherti

Abstract: Kounis syndrome (KS) is a condition characterized by an allergic reaction leading to an acute coronary syndrome. It was initially identified and reported by Kounis and Zavras in 1991 and is alternatively referred to as "allergic angina syndrome" or "allergic myocardial infarction". The initial case documenting an acute myocardial infarction along with urticaria, reported in 1950, involved a 49 - year - old man who was undergoing treatment with 300, 000 units per day of penicillin in oil [2]. KS can be provoked by a variety of factors, and ongoing research continues to reveal additional triggers. Among the most prevalent triggers of KS were antibiotics, accounting for 27.4% of cases, closely followed by insect bites at 23.4% [3], contrast media has been identified as the causative trigger in nearly 6% of the documented KS cases. We are reporting a case of KS resulting from exposure to contrast dye during a percutaneous coronary intervention (PCI).

Keywords: Iodine contrast, allergy, coronary vasospasm, Kounis syndrome, coronary angiography

How to Cite?: Tanae EL GHALI, Najlae Belharty, Zakaria Choho, Fatima Azzahra Benmessaoud, Latifa Oukerraj, Mohamed Cherti, "Kounis Syndrome: Unveiling Allergic Triggers for Acute Coronary Events - A Case Study of Contrast Dye Induced Reaction during Percutaneous Coronary Intervention", Volume 12 Issue 8, August 2023, International Journal of Science and Research (IJSR), Pages: 1747-1750, https://www.ijsr.net/getabstract.php?paperid=SR23816154221, DOI: https://dx.doi.org/10.21275/SR23816154221