Downloads: 5 | Views: 102 | Weekly Hits: ⮙1 | Monthly Hits: ⮙2
Research Paper | Orthopaedic Surgery | Malaysia | Volume 12 Issue 8, August 2023
Survival Rates, Risk Factors and Complications of Surgically Treated Metastatic Disease of the Spine: A Retrospective Study of a Single Center Experience from Southern Malaysia
Wan Zainuddin WAR [3] | Kamal AB | MN Faiz M | Jayamalar T | Saadon I [3]
Abstract: Background: Surgical intervention is the recommended treatment for mechanical and neurological instability in spine metastasis, but there are no published data on our population. Objectives: This study aims to investigate the survival of our local patients with spine metastasis who have undergone surgery, in addition to the associated risk factors and complications. Methods: A retrospective analysis (n=23) of surgically treated metastatic spine disease at a single center in southern Malaysia from 2017 to 2022. Patients' demographics, comorbidities, primary cancer type, complications, pre- and postoperative pain scores, and neurological status were among the data collected. The use of Tokuhashi score, Karnofsky performance scale, and the SINS score was examined. Results: The mean age at surgery was 58.2 (10.09) years and the mean survival time was 25.37 (95%CI= 16.17 - 34.56) months. Serum albumin of over 3.5g/dL was statistically significant in survival with a p-value of 0.022, whereas serum protein was not. Six (26.1%) showed no improvement whereas seventeen (73.9%) had pain relief. Three (13%) showed neurologic improvement, while twenty (87.0%) did not. Preoperative good neurological function significantly improved survival relative to worse Frankel grades (p-value 0.033). Mantel-Cox indicated no statistical significance for the other factors. Five (21.74%) had postoperative complications. Conclusions: Our surgically treated spine metastases patients' survival rates vary. Postoperative survival was statistically significant with preoperative albumin levels >3.5g/dL and good Frankel grade. Tokuhashi scoring and Karnofsky scale helped determine surgery candidates.
Keywords: spine metastasis, survival rate, serum albumin, surgical complications
Edition: Volume 12 Issue 8, August 2023,
Pages: 1363 - 1368