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Doctoral Thesis | Anaesthesiology | Volume 12 Issue 7, July 2023 | Pages: 2141 - 2146 | India
Randomised Double Blind Study for Comparison of Dexmedetomidine V/S Midazolam for Reduction of Incidence of Delirium Post Cardiac Surgery
Abstract: Background: Delirium is a neurobehavioral syndrome caused by the transient disruption of normal neuronal activity secondary to systemic disturbances. Objective: To Compare dexmedetomidine VS midzolam for reduction of incidence of post valvular cardiac surgery delirium. Methods: Patients underwent elective cardiac surgery with a standardrized intraoperative anesthesia protocol, followed by random assignment to one of two postoperative sedation protocols: dexmedetomidine, or midazolam. Results: Dexmedetomidine group (1/30) observed lesser incidence of delirium in comparison to midazolam group (12/30). Conclusion: Dexmedetomidine is a better drug to decrease the incidence of delirium post cardiac surgery over midazolam, with more haemodynamic stability and early extubation time.
Keywords: Delirium, neurobehavioral syndrome, transisent disruption, neuronal activity
How to Cite?: Dr Ajay Sharma, Dr Reema Meena, "Randomised Double Blind Study for Comparison of Dexmedetomidine V/S Midazolam for Reduction of Incidence of Delirium Post Cardiac Surgery", Volume 12 Issue 7, July 2023, International Journal of Science and Research (IJSR), Pages: 2141-2146, https://www.ijsr.net/getabstract.php?paperid=SR23726023212, DOI: https://dx.doi.org/10.21275/SR23726023212