To Evaluate the Levels of Antioxidants Enzymes in Albino Rat Liver Tissue by Injecting Doxorubicin and Antioxidants Separately and in Combination
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 0 | Views: 246

Research Paper | Zoology | India | Volume 12 Issue 7, July 2023 | Popularity: 4.7 / 10


     

To Evaluate the Levels of Antioxidants Enzymes in Albino Rat Liver Tissue by Injecting Doxorubicin and Antioxidants Separately and in Combination

B. Vijayudu, M. Ravi Naik, K. Kalindhar Basha, M. Jaya Chandrudu, A. Venkata Mohan Naidu, P. Ramesh Kumar


Abstract: Doxorubicin is a anticancer drug, it is used in treatment of cancer through chaemotherapy, its effect mainly on cancer cells and also this produce some side effects. for reducing the adverse effects i was used some antioxidants with Dox combination and individually. In this study i was used in 20 mg/kg wt of Doxorubicin and 80 mg/kg wt of Vitamin E, 40 IU/kg wt of Vitamin A individually and in combination over 10weeks (weekly-Doses) on Albino rat Liver. Some antioxidant enzymes such as Superoxide Dismutase, Catalyse, Glutathione Peroxidase, Glutathione Reducatase, Glutathione-S-Transferase levels were estimated in the liver tissue of albino rat. The data of these enzymes I will show in result table from this result. It is reported that the antioxidants like Vitamin E, K reduce the Doxorubicin altered enzyme levels. It is used for cancer studies for better understanding.


Keywords: Liver Tissue, Doxorubicin, Antioxidant Enzymes, Vitamin E, and Vitamin A


Edition: Volume 12 Issue 7, July 2023


Pages: 866 - 872


DOI: https://www.doi.org/10.21275/SR23708210511



Make Sure to Disable the Pop-Up Blocker of Web Browser


Text copied to Clipboard!
B. Vijayudu, M. Ravi Naik, K. Kalindhar Basha, M. Jaya Chandrudu, A. Venkata Mohan Naidu, P. Ramesh Kumar, "To Evaluate the Levels of Antioxidants Enzymes in Albino Rat Liver Tissue by Injecting Doxorubicin and Antioxidants Separately and in Combination", International Journal of Science and Research (IJSR), Volume 12 Issue 7, July 2023, pp. 866-872, https://www.ijsr.net/getabstract.php?paperid=SR23708210511, DOI: https://www.doi.org/10.21275/SR23708210511

Similar Articles

Downloads: 3 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Doctoral Thesis, Zoology, India, Volume 12 Issue 7, July 2023

Pages: 902 - 906

Impact of Vitamin C Supplementation in BPA Induced Swiss Albino Mice (MUS MUSCULUS)

Kather Bee S, Dr Sendhilvadivu M

Share this Article

Downloads: 3 | Weekly Hits: ⮙2 | Monthly Hits: ⮙3

Research Paper, Zoology, India, Volume 13 Issue 6, June 2024

Pages: 1846 - 1851

Evaluation of Antioxidant Role of Trigonella Foenum Graecum in Alloxan Induced Diabetic Wistar Albino Rats

E. Kavitha, Dr. M. Sendhilvadivu

Share this Article

Downloads: 112

Research Paper, Zoology, India, Volume 6 Issue 6, June 2017

Pages: 1258 - 1261

Phytochemical Investigation of the Plant Solanum nigrum L. used in Traditional Medicine from the Local Area of Bhopal

Romana Rashid, Muzaffer Hussain Wani, Sangeeta Devi

Share this Article

Downloads: 115

Research Paper, Zoology, India, Volume 4 Issue 9, September 2015

Pages: 881 - 884

Antioxidant Activity of Root of Achyranthes Aspera and its Comparison with Melatonin in Recovery of Oxidative Stress

Nisreen Husain, Anil Kumar

Share this Article

Downloads: 118

Research Paper, Zoology, India, Volume 6 Issue 5, May 2017

Pages: 1050 - 1056

Protective Effect of Vitamin C on Carbon Tetrachloride Administered Toxicity in Lungs of Mice

Sushma Sharma, Sonika Chauhan

Share this Article
Top