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Comparative Studies | Anaesthesiology | India | Volume 12 Issue 7, July 2023
Comparative Study of 0.125% Bupivacaine and 0.2% Ropivacaine by Combined Spinal-Epidural Technique for Labour Analgesia
Ayesha Begum Shaik
Abstract: Introduction: Intrathecal fentanyl is useful in a distressed parturient to facilitate fast pain relief and better positioning for epidural catheter placement. Many pharmacologic studies claim that Epidural ropivacaine has prolonged duration of sensory block and less motor block compared to bupivacaine and hence we hereby design study to compare 0.125% bupivacaine and 0.2 % ropivacaine for efficacy of analgesia in terms of maximum duration of analgesia, top - up requirements and to look for any associated complications. Aims and objectives: To compare efficacy between epidural bupivacaine and ropivacaine, top - up requirements in labor analgesia. Materials and methods: A total of 60 patients belonging to ASA I and II aged 18 - 35 years were randomized into two groups. Group B received intrathecal 25 mcg fentanyl + 10ml of 0.125% Bupivacaine epidurally (2.5ml of 0.5 % Bupivacaine with 7.5 ml NS). Group R received intrathecal 25mcg fentanyl + 10ml of 0.2 % Ropivacaine epidurally (3ml of 0.75 % with 7ml NS). Pain was assessed using Numeric rating score (NRS) and top - up doses are repeated when numerical pain score is ? 5. Results: Group R had prolonged effective analgesia and require lesser number of epidural doses in 24hrs as compared to Group B (P value 0.002 and 0.011 respectively). There were no significant differences between groups considering time to reach maximum analgesia and NRS after Combined Spinal Epidural Analgesia (CSEA). None of the subjects in Group B and R had Maternal Hypotension, Maternal Paraesthesia and Fetal bradycardia. There was slight increase in instrumentation for delivery.
Keywords: Anesthetics, Local, Analgesics, Opioid, Analgesia, Obstetrical, Analgesia, Epidural
Edition: Volume 12 Issue 7, July 2023,
Pages: 729 - 734