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Research Paper | Medical Science | Indonesia | Volume 12 Issue 7, July 2023

Description of the Mortality Rate of Hypercoagulation, Hypocoagulation, and Normocoagulation Patients in the ICU of Hasan Sadikin Bandung, Hospital

Dewi Yuliana Fithri | Tinni Trihartini Maskoen | Ezra Oktaliansah

Abstract: Introduction: Coagulopathy is a complication of sepsis that is often associated with increased mortality. Examination of conventional coagulation tests is considered unable to assess the function of the coagulation cascade as a whole, but thromboelastography is. Thromboelastography can differentiate septic coagulopathy into hypercoagulation, normocoagulation, and hypocoagulation, but this examination is rarely performed. For this reason, the aim of this study was to describe the mortality features of sepsis patients with hypercoagulation, hypocoagulation, and normcoagulation. Materials &Methods: Descriptive study with research locations in the ICU, Dr. Hasan Sadikin Bandung. The sample for this study was sepsis patients with consecutive sampling. Sample collection begins in September?November 2022. The sample size for this study is total sampling. Data analysis using IBM SPSS Statistics for Windows, version 21 The analysis was carried out univariately, and categorical data will be assessed in the form of a percentage, while numerical data will use the mean or standard deviation if the data is normally distributed. If the data is not normally distributed, use the median or interquartile range. Results: About 86 sepsis patients were analyzed in this study. In terms of coagulation disorders, the most common in this study were 73.2% hypercoagulation, 17.4% normcoagulation, and 19% hypocoagulation. The highest mortality of sepsis patients was in the hypocoagulation group at 50%, normcoagulation at 40%, and hypercoagulation at 34.9%. However, the highest mortality was in the 50% hypocoagulation group compared to the other groups. Discussion: Coagulopathy is an organ failure with high mortality rates. The overall cascade of coagulopathic disorders cannot be established by conventional hemostatic examination, but thromboelastography can assess the overall coagulopathy. Hypocoagulation in sepsis has a higher mortality rate than hypercoagulation and normcoagulation disorders.

Keywords: Coagulation disorders in sepsis, Mortality, Thromboelastography

Edition: Volume 12 Issue 7, July 2023,

Pages: 520 - 524