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Research Paper | Zoology | India | Volume 12 Issue 6, June 2023
Tebuconazole Induced Biochemical Alteration in Serum of Cyprinus carpio (L.1758)
Rimpy | Sushma Sharma 
Abstract: In the present study we investigate the effect of azole fungicide tebuconazole on the serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) activity and protein level in Cyprinus carpio (L., 1758). Tebuconazole commonly known as Folicur, a triazole fungicide is a broad - spectrum systemic fungicide widely used in agricultural fields across the world. Tebuconazole causes detrimental impacts onthe aquatic environment over a long period andhas toxic effects on aquatic organisms. The fish C. carpio (L.1758) have been used as indicator organisms for the determination of toxicity in an aquatic environment. After acclimatization in laboratory conditions, the fish had been divided into three groups, each of which include 6 fish. Group I were kept in a normal water environment serve as control and those in Groups II and III were in 6.47 and 8.09 ?L/L tebuconazole added water tanks, respectively, for 20 days. Blood samples were taken from the anal vein of the fish and serum were collected. Then, ALT, AST, and ALP activities and protein levels were analyzed. While protein level decreased in tebuconazole treated groups compared to Group I, increases were determined in terms of ALT, AST, and ALP activity. In conclusion, it was found that fungicide tebuconazole exposure caused significant changes in serum enzymatic activities and protein levels of Cyprinus carpio. The increase in AST and ALT levels could be associated with liver function changes as a result of fungicide exposure to the fish.
Keywords: Cyprinus carpio, Tebuconazole, ALT, AST, phosphatase
Edition: Volume 12 Issue 6, June 2023,
Pages: 1207 - 1211