Clinical and Biochemical Profile and Outcome in Scrub Typhus Positive Patients

Nidhi Chaurasia, Azhar Ali Khan, Sudheer Yadav

Abstract: Introduction: Scrub typhus (Tsutsugamushi disease) is an acute (1 week (86.52%), altered sensorium (43.82%), and icterus (59.55%) were the predominant clinical features. Hepatomegaly and splenomegaly were also reported. Diabetes (n=7) and hypertension (n=5) were the common comorbidities. The majority of the patients (n=41) had GCS of 11 - 15, of which 100% were survivors. Mortality (73.34%) was significantly found in those withGCS 3 - 6. Overall, the fatality was 14.60%. A significant difference was noted in haematological parameters. The majority of the non - survivors had total serum bilirubin>3mg/dl (n=6), creatinine>3mg/dl (n=8). A significantly negative correlation was also noted between Outcomes and serum creatinine (r= - 0.3569). Furthermore, the sensitivity (69.23%) and specificity (59.21%) at a cut - off value of Serum Creatinine

Keywords: Scrub Typhus, Febrile illness, Splenomegaly, Platelet count, Mortality

How to Cite?: Nidhi Chaurasia, Azhar Ali Khan, Sudheer Yadav, "Clinical and Biochemical Profile and Outcome in Scrub Typhus Positive Patients", Volume 12 Issue 6, June 2023, International Journal of Science and Research (IJSR), Pages: 903-909, https://www.ijsr.net/getabstract.php?paperid=SR23605133325, DOI: https://dx.doi.org/10.21275/SR23605133325

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