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Research Paper | Obstetrics and Gynecology | India | Volume 12 Issue 5, May 2023
Comparative Study of Oral Ferrous Sulphate and Intravenous Iron Sucrose for Iron Deficiency Anaemia in Pregnancy
Dr. Sumer Singh Gurjar | Dr. Badari Lal Patidar | Dr. Vinita Gupta | Dr. Priyanka Meena [2] | Dr. Preeti Goyal [2] | Dr. Kumkum Gupta
Abstract: ound: Iron deficiency anaemia (IDA) in Pregnancy can cause placental problems, fetal death, infections, and low iron stores in newborns. It takes weeks for oral iron to raise haemoglobin and months to replenish the iron stores in the body. Therefore many women fail to comply with such prolonged therapy. Alternative treatment methods for anemia include intravenous (IV) iron therapy or blood transfusion. In present study we have used iron sucrose for parenteral iron therapy. This study was undertaken to evaluate the efficacy, safety and acceptability of intravenous iron sucrose complex in comparison to oral ferrous sulfate in mild to moderate iron deficiency anemia during pregnancy. Material and methods: Type of study; Comparative Prospective, Interventional study. Current study was conducted in department of Obstetrics and Gynaecology, Govt. Medical College Kota from February 2021 to December 2022. A total 200 pregnant woman attending Antenatal clinic between 16 to 32 weeks were randomly assigned either to intravenous or to oral iron group. Results: Statistically significant Hb and serum ferritin increase in both the groups from pre - treatment to post 4 week. Our study revealed that at 4 week and 6 week Hb was significantly more increase in group IV compare to group Oral iron and out of the 100 participants in IV group, maximum 97 had no side effect, Out of the 100 participants in group Oral, maximum 88 had no side effect and this difference was statistically insignificant. Conclusion: For women with mild to moderate anemia, intravenous iron therapy under supervision is a superior option then oral iron. intravenous iron sucrose is safe & highly effective, for the treatment of iron deficiency anemia. Because of rapid absorption, iron sucrose treatment is more successful in attaining the better results than oral iron.
Keywords: Iron Deficiency Anaemia, pregnancy, oral ferrous sulfate, Serum ferritin, Haemoglobin
Edition: Volume 12 Issue 5, May 2023,
Pages: 2321 - 2324