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Study Papers | Health and Medical Sciences | India | Volume 12 Issue 5, May 2023
CMV Hepatitis in an Immunocompetent Young Pregnant Female: A Rare Cause for Maternal Mortality
Suman Gupta | Ghotekar L. H. | Anu Goswami | Ramesh Aggarwal 
Abstract: Cytomegalovirus is one of the TORCH infections. TORCH infections classically comprise toxoplasmosis, rubella, cytomegalovirus, herpesvirus, hepatitis viruses, human immunodeficiency virus, Treponema pallidum and other infections, such as varicella, parvovirus B19, and enteroviruses. Cytomegalovirus can be transmitted from mother to child in utero, intrapartum or during breastfeeding. Here we arepresenting the case of immunocompetent young pregnant female with 18 weeks period of gestation who presented in hospital with complaints of fever, vomiting, yellowish discoloration of eyes and urine with altered sensorium. She was being evaluated as a case of acute onset hepatitis with coagulopathy with hepatic encephalopathy (fulminant hepatic failure). While other viral markers were negative, IgM CMV serology came out to be positive. In spite of prompt proper management, she deteriorated further and succumbed to the illness. It stresses the importance that one should keep high degree of suspicion of CMV in immunocompetent individual as a rare cause of fulminant hepatitis in pregnancy.
Keywords: Cytomegalovirus, TORCH, immunocompetent, pregnancy, viral fulminant hepatitis
Edition: Volume 12 Issue 5, May 2023,
Pages: 1712 - 1714