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Analysis Study Research Paper | Medical Science | India | Volume 12 Issue 5, May 2023
Effect of Body Mass Index on in Vitro Fertilization Outcomes
Aishwarya Choudhari | Kundavi Shankar [8] | Yamini Asokan [5] | Geetha .V [3] | Rashmi [144] | Nithya Naaram6 | Hema Niveda. KR [2]
Abstract: Introduction: Several factors can affect the outcomes of IVF, such as maternal age, ovarian reserve, and the quality of embryos. Recently, there has been growing evidence that suggests body mass index (BMI) could also influence the success rates of IVF. BMI is a measure of body fat based on height and weight and has been associated with several health problems, including infertility. However, the exact correlation between BMI and IVF outcomes is still under investigation. Materials and methods: This was a retrospective research done on infertile women who underwent IVF at Madras Medical Mission and were IRM OPD patients. The 220 women who underwent IVF therapy between 2018 and 2021 were included in the study, and their BMI was noted at the start of the procedure. They included AMH, AFC, FSH, luteinizing hormone (LH), and estradiol (E2). All of the study's participants experienced antagonist protocol - controlled ovarian hyper stimulation. Results: 42 people (19.1%) were in the normal weight range, 90 people (40.9% were overweight), and 71 people (32.3%) were obese. Regarding age, the length of infertility, and both female and male causes of infertility, all three groups were comparable. Day 2 LH/FSH levels, endometrial thickness, gonadotrophin needs, oocyte quality, fertilisation, cleavage rates, number of good quality embryos, and clinical pregnancy rates were all comparable between the three groups. Conclusion: Increased body mass index in women does not seem to have a negative impact on the success of IVF. Nonetheless, preconception counselling for obese women is essential because losing weight lowers the risk of problems associated to pregnancy.
Keywords: Obesity, Subfertility, Invitro - fertilization, Body mass index
Edition: Volume 12 Issue 5, May 2023,
Pages: 827 - 831