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Comparative Studies | Medicine Science | India | Volume 12 Issue 4, April 2023

Comparison of Dexmedetomidine and Clonidine as an Adjuvant to Bupivacaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgeries

Devulapalli Janardhana Pradeep | Subhaprada Satapathy | Rasulata Swain | Ayesha Pattnaik

Abstract: Background: Various additives are added with local anaesthetics to lengthen the quality of block in regional anaesthesia. compared clonidine and dexmedetomidine as an adjunct to bupivacaine in supraclavicular brachial plexus block to compare the onset and duration of sensory and motor block. Aim: To compare the effectiveness of clonidine and dexmedetomidine as adjuvant in brachial plexus block by supraclavicular approach for lengthening of sensory and motor blockade and duration of analgesia. Materials and methods: Sixty ASA Grades I and II patients posted for orthopaedic surgeries of the upper limb under supraclavicular brachial plexus block were divided into two groups in a randomized, double - blind manner. Patients were divided randomly into two groups. In Group BC (n = 30), 39 ml of 0.25% bupivacaine plus 1 ml (1 ?g/kg) clonidine and in Group BD (n = 30), 39 ml of 0.25% bupivacaine plus 1 ml (1 ?g/kg) dexmedetomidine Are given. The onset and duration of sensory and motor block and duration of analgesia were studied in both the group. Discussion: In our study, we compared the addition of clonidine (1 ?g/kg) and dexmedetomidine (1 ?g/kg) to bupivacaine in SCBP block. The study revealed that onset time for both sensory and motor blocks after the supraclavicular brachial plexus block using either clonidine or dexmedetomidine with bupivacaine were similar. But, dexmedetomidine gave longer duration of both motor and sensory blocks and lengthened duration of analgesia. dexmedetomidine group had better quality of anaesthesia. Conclusion: our study demonstrated that addition of dexmedetomidine to bupivacaine in supraclavicular brachial plexus block prolonged the duration of analgesia and improved the quality of anaesthesia as compared to clonidine with better hemodynamic stability and less side effects, that makes dexmedetomidine an better choice as an adjuvant to bupivacaine for supraclavicular brachial plexus block.

Keywords: Clonidine, dexmedetomidine, bupivacaine, supraclavicular brachial plexus block

Edition: Volume 12 Issue 4, April 2023,

Pages: 1146 - 1149