International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

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Research Paper | Pathology | India | Volume 12 Issue 4, April 2023

Histopathological Spectrum of Lesions of Heart - An Autospsy Based Study in Tertiary Care Centre

Dr. Yash Saxena | Dr. Jyoti Priyadarshini Shrivastava | Dr. Saurabh Shrivastava | Dr. Rajesh Gaur

Abstract: Introduction: Autopsy histopathology is useful in conditions of undiagnosed or suspected cases to confirm the diagnosis both in routine and medicolegal cases. The role of pathologist is to study the disease process which lead to death and to establish the cause of death. Incidence of ischemic heart disease in India has increased to about 10 percent. The occurrence of sudden death presents a great challenge to the general autopsy pathologist and as cardiac autopsy is the main diagnostic tool to study various histomorphological changes in normal and diseased heart. Objective: The aim of this study was to analyze the various heart lesions histopathologically i.e both on gross and microscopy on heart received after autopsy at department of pathology, Gajra Raja Medical College, Gwalior during the period of 1.5 years. Method: A prospective study was done on 131 specimens of heart received during 2021 - 22. All relevant histopathological details pertaining to gross and microscopic diagnosis were comprehensively studied. Result: Out of total received 131cases, in 26.66% of cases, Heart was normal grossly and in 19.8% of cases Heart was normal microscopically, while in 76.33% of cases, Heart was diseased grossly and 80.15% of cases Heart was diseased microscopically. Most common Microscopic Lesion in left ventricle was [Muscle Hypertrophy] with 41 (31.29%) cases. Most common Right Ventricular Lesions was found to be [MUSCLE HYPERTROPHY] with 21 [16.03%] cases. On examining left coronary artery, [ATHEROSCLEROSIS] was present in maximum number of cases; 10 [47.61%], while in Right coronary artery, [ATHEROSCLEROSIS] was the most common lesion being present in; 08 [34.78%] cases. Conclusion: The Study of Autopsy Specimen histologically which include both gross and microscopic examination is a simple, convenient and reliable method which gives precise histological diagnosis which may have led to mortality or morbidity of deceased. It is highly imperative to subject the whole heart of all medicolegal autopsies for histopathological examination in order to know or to rule out various pathologies.

Keywords: Autopsy Pathology, Left Ventricle, Right Ventricle, Left Coronary Artery, Right Coronary Artery

Edition: Volume 12 Issue 4, April 2023,

Pages: 709 - 714

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