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Research Paper | Pathology | India | Volume 12 Issue 3, March 2023

Study of Pattern of Histopathological Lesions in Nephrectomy Specimens in a Tertiary Care Hospital

Dr. Barri Jyothi Swaroopa

Abstract: Introduction: Nephrectomy, either partial, complete or radical, is a surgical procedure where kidney is removed in patients with an advanced kidney damage due to different renal diseases, injuries or congenital conditions. These diseases include serious kidney infections and inflammations like chronic pyelonephritis and glomerulonephritis, benign and malignant kidney tumours and above all from a donor for renal transplantation where even a healthy kidney is removed. Though with the advanced imaging technologies like CT, MRI and ultrasound near accurate preoperative diagnosis can be made but histopathological study remains the gold standard. This study has been taken up to analyse the nephrectomy specimens received in the last two years and find out the various histology types, their relative frequency, this being a tertiary care hospital. Results: A total of 24 nephrectomy specimens were studied, received over a period of 2 years at this laboratory. Clear cell Renal cell carcinoma (RCC) was the most frequent constituting 6 cases, whereas 2 cases were Papillary RCC, 1 case was chromophobe variant, and 1 case was sarcomatoid variant, 8 cases were Chronic pyelonephritis, followed by 6 cases of hydronephrosis. Conclusion: It is concluded that both non - neoplastic pathologies and malignant renal tumours were the indication for nephrectomies at this tertiary care centre and incidence of malignant renal tumours has been found to be relatively more common in comparison to non - neoplastic pathologies ostensibly due to the fact that this centre being a cancer referral centre.

Keywords: Renal cell carcinoma (RCC), Nephrectomy, neoplastic, non - neoplastic

Edition: Volume 12 Issue 3, March 2023,

Pages: 1218 - 1220