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Comparative Studies | Anaesthesiology | India | Volume 12 Issue 3, March 2023

Comparative Study of Epidural Levobupivacaine 0.5% and Ropivacaine 0.75% on Lower Limb Orthopaedic Surgeries

Saha Gunjan | Deka Bipul ^[3] | Swargiri Kannauj ^[3] | Dr. Kiran Sonowal

Abstract: Background and Aims: The aim of the study was to compare the onset time and duration of epidural anaesthesia produced by levobupivacaine and ropivacaine for lower limb orthopaedic surgeries and to determine postoperative analgesia. Methods: 90 patients of ASA grade I and II planned for elective lower limb orthopedic surgeries were divided into two groups randomly. Group I (n=45): received 15ml 0.5% levobupivacaine; Group II (n=45): received 15ml 0.75% epidurally. Onset time and regression of motor and sensory block and postoperative analgesia were evaluated. Results: onset of sensory block with levobupivacaine was 18.51?2.77 minutes and with ropivacaine was 16.04?2.31 minutes (p<0.001). Duration of sensory block with levobupivacaine was 164.09?8.88 minutes and with ropivacaine was 172.26?4.03 minutes (p<0.0001). Onset of motor block with levobupivacaine was 28.07? 4.01 minutes and with ropivacaine was 23.07?2.77 minutes (p < 0.001). Duration of motor block with levobupivacaine was 143.51? 5.69 minutes and with ropivacaine was 141.78?3.35 minutes (p=0.0819). Time for first rescue analgesia with levobupivacaine was 276.82?41.29 minutes and for ropivacaine was 376.62?45.82 minutes (p<0.0001). Conclusion: Onset of sensory and motor block was faster and duration of sensory block was longer with ropivacaine than levobupivacaine. Postoperative analgesia was better with Ropivacaine.

Keywords: Epidural Anaesthesia, levobupivacaine, ropivacaine

Edition: Volume 12 Issue 3, March 2023,

Pages: 325 - 328