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Comparative Studies | Anaesthesiology | India | Volume 12 Issue 3, March 2023

Comparative Study of Effect of Preoperative Ketamine and Magnesium Sulphate Nebulization in Reducing the Incidence and Severity of Post Operative Sore Throat after Tracheal Intubation A Double Bind Randomized Control Study

Kapil Sharma ^[3] | Virendra Malav ^[2] | S. P. Chittora ^[8]

Abstract: Background: Routine tracheal intubation for elective surgical procedures can result in pathological changes, trauma and nerve damage which may also account for postoperative throat symptoms which is considered as a minor complication, but is a valid reason of dissatisfaction and morbidity among patients. We studied to evaluate the role of preoperative ketamine and MgSO4 nebulization on incidence and severity of postoperative sore throat. Material and methods: This study was conducted in 90 patients of either sex divided in three groups (Group k n=30, Group m n=30 and Group C n=30) was done. Group k patients were received ketamine nebulisation Group M received MgSO4 nebulization and Group C nebulized with normal saline Sore throat assessment and hemodynamic recording were done at pre - nebulisation, pre - induction and immediate after recovery 0 h, 2, 4, 6, 8, 12, 24 h post operatively. these groups was compared using one - way analysis of variance (ONE ?WAY ANOVA) and difference between the groups compared using unpaired T - Test. Results: Ketamine nebulation prevent incidence of POST in comparison of MgSO4. Conclusion: We concluded that preoperative nebulization for prevention of POST with ketamine can be safe and effectively used for patients among undergoing general surgery under General Anaesthesia with tracheal intubation.

Keywords: Nebulisation, Ketamine, Mgso4

Edition: Volume 12 Issue 3, March 2023,

Pages: 13 - 16